Fresenius Medical Care Fresenius Kabi Fresenius Helios Fresenius Vamed
in new markets - Fresenius Medical Care
for further growth - Fresenius Kabi
for better health - Fresenius Helios
for greater efficiency - Fresenius Vamed
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Seizing opportunities > in new markets

Asia is an important growth market for Fresenius Medical Care. Approximately 620,000 patients with chronic kidney failure are currently being treated in this region, and every year this number increases by about 10 to 11%. We will continue to take advantage of this growth potential. The significant demand for dialysis services offers substantial opportunities to expand our network of clinics in the Asian countries.

In 2008, Fresenius Medical Care achieved sales of US$ 606 million in the Asia-Pacific region. Our goal is to continue our strong organic growth and to increase sales to more than US$ 800 million in constant currency by 2010.

FRESENIUS MEDICAL CARE IN ASIA
  2008 2007 Change
Sales (in million US$) 606 541 12%
Employees (December 31) 3,558 3,095 15%
Dialysis patients (December 31) 9,158 7,789 18%
Dialysis treatments (million) 1.34 1.21 11%
Dialysis clinics (December 31) 125 105 19%
 

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Seizing opportunities > for further growth

With the acquisition of APP Pharmaceuticals, Fresenius Kabi has achieved a leading position in the global market for intravenously administered generic drugs. APP Pharmaceuticals has a strong drug registration portfolio pending and over 70 products under development, opening up new growth opportunities.

At the same time, we are seizing the opportunity of introducing selected Kabi products into the US, with initial focus on parenteral nutrition. We are also planning to launch selected APP IV drugs outside the US.

APP PHARMACEUTICALS IN FIGURES
  2008
Sales US$ 777 million
EBITDA, adjusted* US$ 317 million
EBITDA margin, adjusted* 40.8%
Employees (December 31, full-time equivalent) 1,487
Production facilities 3
Produkte >100
Number of products ~17%
 

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Seizing opportunities > for better health

At Fresenius Helios, our commitment is to provide the highest medical quality and care. We aim to offer advanced and proven best-in-class diagnosis and treatment methods for the benefit of our patients. We continuously invest in high-quality, state-of-the-art medicine, and aim to measure and improve the quality of medical care.

Our target ist that our quality indicators should be better than the German average. With a mortality rate of SMR < 1, this was accomplished, among others, for major illnesses shown below.

HELIOS QUALITY INDICATORS
Indications/
standardized mortality rate (SMR)*
2008
SMR
2007
SMR
Acute myocardial infarction 0.73 0.79
Heart failure 0.73 0.85
Stroke 0.83 1.01
Acute cerebral infarction 0.81 0.99
Pneumonia 0.71 0.85
 

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Seizing opportunities > for greater efficiency

Fresenius Vamed is a leading international provider of services in the planning, construction, and management of health care facilities. Our complete value chain and our more than 25 years of international experience are key to providing effective support for hospitals at every stage of their life cycle, and thus contributing towards their successful operating performance. For us, each project is another opportunity to prove our competence.

Hospitals face the dual challenge of increasing efficiency and reducing expenditure. We support hospitals by offering comprehensive process know-how and by taking over medical-technical services and management functions.

VAMED SERVICES
   
Service contracts* for   140 clinics
  ~ 50,000 beds
among others:  
Vienna General Hospital and University Clinics (AKH) ~ 2,100 beds
Charité Hospital Berlin ~ 3,200 beds
University Clinic Hamburg-Eppendorf ~1,370 beds
Prince Court Medical Center, Kuala Lumpur ~ 330 beds
Al Ain Hospital, Abu Dhabi ~ 450 beds
 

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For the fiscal years 2008 and 2007, the number and value of convertible bonds and stock options issued is shown in the following table:

  Long-term incentive components
 
Stock options and convertible bonds1)
   Number  Value in thousand €
  2008 2007 2008 2007
Dr. Ulf M. Schneider 51,600 43,860 815 838
Rainer Baule 25,800 21,930 408 419
Dr. Francesco De Meo
(since January 1, 2008)
25,800  
408  
Andreas Gaddum
(until December 31, 2007)
 
21,930  
419
Dr. Jürgen Götz (since July 1, 2007) 25,800 21,930 408 419
Dr. Ben Lipps 99,600 99,600 976 967
Stephan Sturm 25,800 21,930 408 419
Dr. Ernst Wastler
(since January 1, 2008)
25,800  
408  
Total 280,200 231,180 3,831 3,481
   

The stated values of the stock options granted to members of the Management Board in the fiscal year 2008 correspond to their fair value at the time of grant, namely a value of € 15.80 (2007: € 19.11) per stock option of Fresenius SE and € 9.80 (2007: € 9.71) per stock option of FMC-AG & Co. KGaA.

As the financial targets of the year 2008 were achieved, Dr. Ben Lipps is entitled to a stock-based compensation in an amount of € 425 thousand (2007: € 910 thousand). The entitlement is based on the development of the ordinary share of Fresenius Medical Care and has a three years vesting period.

At the end of the fiscal year 2008, the members of the Management Board held a total of 720,900 (2007: 540,300) stock options and convertible bonds of Fresenius SE and 818,411 (2007: 824,280) stock options and convertible bonds of FMC-AG & Co. KGaA.

The development and the status of the stock options of the Management Board in the fiscal year 2008 are shown in the following table:

  Dr. Ulf M.
Schneider
Rainer
Baule
Dr. Francesco
De Meo
Dr. Jürgen
Götz
Dr. Ben
Lipps1)
Stephan
Sturm
Dr. Ernst
Wastler
Total2)
Options outstanding on January 1, 2008                
   number 219,300
135,450
30,000
36,930
824,280
87,720
30,900
540,300
   average
   exercise    price in €
32.62
30.30
49.13
48.86
22.31
39.52
42.05
35.72
Options granted during fiscal year                
   number 51,600
25,800
25,800
25,800
99,600
25,800
25,800
180,600
   average
   exercise
   price in €
53.56
53.56
53.56
53.56
35.49
53.56
53.56
53.56
Options exercised during fiscal year                
   number 0
0
0
0
105,469
0
0
0
   average
   exercise
   price in €
        17.25
     
   average
   stock
   price in €
        35.60      
Options outstanding on December 31, 2008                
   number 270,900 161,250 55,800 62,730 818,411 113,520 56,700 720,900
   average
   exercise
   price in €
36.61 34.02 51.18 50.79 24.57 42.71
47.29 40.19
   average
   re-
   maining
   life in
   years
6.5 6.0 7.4 7.4 3.7 7.1 7.0 6.7
   range of
   exercise
   prices
   in €
13.59
to
57.27
13.59
to 57.27
40.98
to
57.27
29.92
to 57.27
14.47
to 35.49
29.92
to 57.27
21.33
to 57.27
13.59
to 57.27
Exercisable options on December 31, 2008              
   number 131,574 91,584 4,998 6,000 519,611 36,546 10,098 280,800
   average
   exercise
   price in €
22.84 22.17 40.98 35.45 19.55 32.13 30.94 24.72